Isa Kupke, PhD

Postdoctoral Fellow

203 ABNR Bldg
isa.kupke@missouri.edu

Isa Kupke (Née Lambrechts) completed her PhD in Medicinal Plant Science at the University of Pretoria in South Africa. Her research focused on indigenous South African plants for their medicinal value regarding antibiotic resistance of bacteria associated with acne vulgaris, wounds, and prosthetic implant-associated infections. She has a passion for traditional medicine and community development of traditional knowledge holders of these invaluable resources. She works in Dr. Chung-Ho Lin’s Lab.

Google Scholar Profile

Research Foci

  • Indigenous plants and medicinal uses
  • Skin ailments and wounds

Selected Publications

  • Lambrechts, Isa A., Velaphi C. Thipe, Kattesh V. Katti, Vusani Mandiwana, Michel Lonji Kalombo, Suprakas Sinha Ray, Rirhandzu Rikhotso, Arno Janse van Vuuren, Tenille Esmear, and Namrita Lall. “Targeting Acne Bacteria and Wound Healing In Vitro Using Plectranthus aliciae, Rosmarinic Acid, and Tetracycline Gold Nanoparticles.” Pharmaceuticals 15, no. 8 (2022): 933.
  • Lambrechts, Isa Anina, and Namrita Lall. “Traditional usage and biological activity of Plectranthus madagascariensis and its varieties: A review.” Journal of Ethnopharmacology 269 (2021): 113663.
  • Lall, Namrita, A. Blom Van Staden, Sunelle Rademan, I. Lambrechts, Marco Nuno De Canha, James Mahore, Stefan Winterboer, and Danielle Twilley. “Antityrosinase and anti-acne potential of plants traditionally used in the Jongilanga community in Mpumalanga.” South African Journal of Botany 126 (2019): 241-249.
  • Lall, Namrita, Antonios Chrysargyris, Isa Lambrechts, Bianca Fibrich, Analike Blom Van Staden, Danielle Twilley, Marco Nuno De Canha, Carel Basson Oosthuizen, Dikonketso Bodiba, and Nikolaos Tzortzakis. “Sideritis perfoliata (subsp. perfoliata) nutritive value and its potential medicinal properties.” Antioxidants 8, no. 11 (2019): 521.
  • Aumeeruddy, M. Z., Z. Aumeeruddy-Elalfi, H. Neetoo, G. Zengin, A. Blom van Staden, B. Fibrich, I. A. Lambrechts et al. “Pharmacological activities, chemical profile, and physicochemical properties of raw and commercial honey.” Biocatalysis and Agricultural Biotechnology 18 (2019): 101005.
  • Stapelberg, Julanie, M. Nqephe, I. Lambrechts, B. Crampton, and Namrita Lall. “Selected South African plants with tyrosinase enzyme inhibition and their effect on gene expression.” South African journal of botany 120 (2019): 280-285.
  • Lall, Namrita, Navneet Kishore, Bianca Fibrich, and Isa Anina Lambrechts. “In vitro and in vivo activity of Myrsine africana on elastase inhibition and anti-wrinkle activity.” Pharmacognosy magazine 13, no. 52 (2017): 583.

Book Chapters

  • Lambrechts, Isa A., and Namrita Lall. “Phytomedicines Targeting Antibiotic Resistance through Quorum Sensing and Biofilm Formation Associated with Acne Vulgaris.” In Medicinal Plants for Cosmetics, Health and Diseases, pp. 37-59. CRC Press, 2022.
  • Lambrechts, Isa A., Lydia Gibango, Antonios Chrysargyris, Nikolaos Tzortzakis, and Namrita Lall. “Aquatic Plants Native to Europe.” In Aquatic Plants, pp. 241-290. CRC Press, 2020.
  • Lambrechts, Isa A., and Namrita Lall. “Ocimum labiatum.” In Underexplored Medicinal Plants from Sub-Saharan Africa, pp. 211-215. Academic Press, 2020.
  • Lambrechts, Isa A., and Namrita Lall. “Plectranthus ecklonii.” Underexplored Medicinal Plants from Sub-Saharan Africa, pp. 229-233. Academic Press, 2020.
  • Lambrechts, Isa A., and Namrita Lall. “Plectranthus neochilus.” In Underexplored Medicinal Plants from Sub-Saharan Africa, pp. 235-240. Academic Press, 2020.
  • Fibrich, B., Isa Anina Lambrechts, and Namrita Lall. “Nanotechnology and Anti-Ageing Skin Care.” In Natural Medicines, pp. 377-392. CRC Press, 2019.
  • Lambrechts, Isa Anina, Marco Nuno de Canha, and Namrita Lall. “Exploiting medicinal plants as possible treatments for acne vulgaris.” In Medicinal Plants for Holistic Health and Well-Being, pp. 117-143. Academic Press, 2018.

Patents

  • Lambrechts IA, Lall N. Anti-Acne Pharmaceutical Composition. Patent. South African provisional patent application ZA 2018/08307 (2018, 10 Dec). PCT application filed PCT/IB2019/060604 (2019, 10 Dec).

Awards

  • Dr. Willmar Schwabe Research Scholarship (2021) – Society for Medicinal Plant and Natural Product Research. Award winner.
  • South African Women in Science Award (2018) – DST-Albertina Sisulu Fellowship (Doctoral) Award winner.
  • Gauteng Department of Agriculture and Rural Development – Biotech Fundi Awards (2017-2018) finalist.

Explore more resources from Dr. Kupke and the Center for Agroforestry team.

READ

Take a look at the Center for Agroforestry’s free technical guide for growing pecans.

Download

WATCH

Learn about one of the Center’s elderberry genotype by environment study, led by grad student Sydney Moore.

Watch on YouTube

LISTEN

This episode of The Agroforestry Podcast explores how fungi can play an important role on farms with trees.

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